Research in pharmaceutical sciences · 2022
Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L.
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Vakili Narges, Esmaeilifallah Mahsa, Dinani Masoud Sadeghi
Аннотация
BACKGROUND AND PURPOSE: Phytochemically, Allium species are a rich source of important secondary metabolites especially steroidal saponin and sapogenins, flavonoids, and sulfur compounds. As a member of this genus, Allium affine, which is locally known as "tareh kouhi", is an endemic plant of middle Asian countries.
EXPERIMENTAL APPROACH: Bulbs of A. affine were collected and air-dried in the shade. The chloroform-methanol (9:1) extract of the sample was subjected to purification by MPLC and HPLC. Structure elucidation of isolated compounds was done using comprehensive spectroscopic methods including 1D-NMR, 2D-NMR, and MS.
FINDINGS/RESULTS: A steroidal saponin structurally related to parillin and a phenylpropanoid glycoside (coniferin) were isolated and identified from the plant chloroform-methanol extract.
CONCLUSION AND IMPLICATION: To the best of our knowledge isolation of these potentially medicinal compounds from A. affine was reported for the first time in this study.
EXPERIMENTAL APPROACH: Bulbs of A. affine were collected and air-dried in the shade. The chloroform-methanol (9:1) extract of the sample was subjected to purification by MPLC and HPLC. Structure elucidation of isolated compounds was done using comprehensive spectroscopic methods including 1D-NMR, 2D-NMR, and MS.
FINDINGS/RESULTS: A steroidal saponin structurally related to parillin and a phenylpropanoid glycoside (coniferin) were isolated and identified from the plant chloroform-methanol extract.
CONCLUSION AND IMPLICATION: To the best of our knowledge isolation of these potentially medicinal compounds from A. affine was reported for the first time in this study.