[Determination of methylcyclohexanol in workplace air by solvent desorption-gas chromatography].

Objective

To establish a gas chromatography method with solvent desorption for the determination of methylcyclohexanol in workplace air.

Methods

In February 2024, the workpace air samples were collected through Neutral silicone tubes, desorbed with ethanol, separated by a polyethylene glycol capillary column modified with nitrophenyl terephthalic acid (DB-FFAP), and then determined by a hydrogen flame ionization detector (FID) .

Results

1-methylcyclohexanol, 3-methylcyclohexanol and 4-methylcyclohexanol show good linear relationships when the mass concentrations are between 1.15-1840.00 μg/ml, and 2-methylcyclohexanol shows good linear relationship when the mass concentration is between 1.16-1860.00 μg/ml (the correlation coefficient r was better than 0.9999) ; the limit of detection (LOD) was 0.23 μg/ml, and the limit of quantification (LOQ) was 0.77 μg/ml, The lowest detection and lowest quantification concentrations were 0.15 and 0.51 mg/m(3) (measured by 1.5 L air sample). The method showed a good average desorption efficiency which was 96.71%-99.47%, and the relative standard deviation (RSD) of within-batches and between-batches were 0.51%-1.25% and 1.20%-2.45%. The air samples could be saved at least 14 d at room temperature and 4 Celsius degree without obvious loss.

Conclusion

This method has the characteristics of high precision, high desorbent efficiency, high sensitivity, and simple operation. It is suitable for the determination of methylcyclohexanol in the air in the workplace.