Journal of medical screening · 2012
Neonatal screening for congenital hypothyroidism in East Azerbaijan, Iran: the first report.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Zeinalzadeh Ali Hossein, Talebi Malihe
Аннотация
OBJECTIVES: To investigate the prevalence of congenital hypothyroidism (CH) among neonates in East Azerbaijan, Iran.
METHODS: A cross-sectional study conducted from 2009 to 2010. Most heel blood samples were taken between three and seven days of birth. Thyroid stimulating hormone (TSH) was tested using the enzyme-linked immunosorbent assay method. Neonates with abnormal screening results (TSH>20 mIU/L, T4<6.5 mg/dL) were re-examined. Data were analysed using SPSS software.
RESULTS: A total of 62,459 infants were screened. Of 1562 re-called subjects (re-call rate 2.5%), 94 cases with CH were detected, yielding a CH prevalence of 1:666 (female:male ratio 1:1.4).
CONCLUSION: The prevalence of CH in East Azerbaijan province is higher in comparison with worldwide levels. These results emphasize the importance of the neonatal screening programme.
METHODS: A cross-sectional study conducted from 2009 to 2010. Most heel blood samples were taken between three and seven days of birth. Thyroid stimulating hormone (TSH) was tested using the enzyme-linked immunosorbent assay method. Neonates with abnormal screening results (TSH>20 mIU/L, T4<6.5 mg/dL) were re-examined. Data were analysed using SPSS software.
RESULTS: A total of 62,459 infants were screened. Of 1562 re-called subjects (re-call rate 2.5%), 94 cases with CH were detected, yielding a CH prevalence of 1:666 (female:male ratio 1:1.4).
CONCLUSION: The prevalence of CH in East Azerbaijan province is higher in comparison with worldwide levels. These results emphasize the importance of the neonatal screening programme.