[Effect of Gastrodia on rotation induced motion sickness in mice].

OBJECTIVE

To observe the effect of Gastrodia on motion sickness induced by rotation in mice.

METHOD: Clockwise and anticlockwise accelerated rotations up to 180 degrees/s for 10 min were used to induce symptoms of motion sickness such as condition taste aversion (CTA), decrease of spontaneous locomotion and impaired ability of space identification in water-maze.

RESULT: Gastrodia could improve the response of CTA, increase spontaneous locomotion, and enhance the ability of learning and memory in water-maze in mice after the rotation.

CONCLUSION

Symptoms of motion sickness induced by rotation could be improved by Gastrodia treatment.