Characteristics of oocyte fertilization and early embryo development in infertile women with different ovarian reserves in the Changde region, China.

This study investigates the correlation between different ovarian reserves and the oocyte fertilization rate as well as early embryo development in the Changde area. A total of 325 infertile women who underwent in vitro fertilization procedure were recruited in the study and classified according to their anti-Müllerian hormone level into 3 groups: low ovarian reserve (LOR), normal ovarian reserve (NOR), and high ovarian reserve (HOR). Compared with LOR, the rate of total fertilization, the number of oocytes retrieved, day 3 good quality embryo and blastocyst formation were found to be significantly increased in NOR and HOR, respectively. These indicators were not significantly different between NOR and HOR. In the Changde area, the serum E2 levels and the number of follicles larger than 14 mm in infertile women on the trigger day significantly increased with higher ovarian reserve, but the ratio of E2 to the number of follicles larger than 14 mm was found to be unrelated to ovarian reserve. A LOR function was observed to reduce the fertilization rate of oocytes, while the early development of embryos was independent of the level of ovarian reserve.