Arquivos de neuro-psiquiatria · 2026
A single-site retrospective cohort on the profile of in-hospital stroke: an alarming sentinel of systemic failures.
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Baston Ana Beatriz Marangoni, Pozzobon Pedro Machry, Loes Italo Merino, Modolo Gabriel Pinheiro, Santos Daniel Fabiano Barbosa Dos, Ferreira Natália Cristina, Bazan Silméia Garcia Zanati, Luvizutto Gustavo José, Bazan Rodrigo, Mendes-Chiloff Cristiane
Аннотация
BACKGROUND: In-hospital stroke is associated with delayed recognition, reduced access to acute treatment, and worse outcomes, particularly in low- and middle-income countries.
OBJECTIVE: To characterize the clinical profile, care processes, and outcomes of patients with ischemic stroke occurring during hospitalization.
METHODS: The present retrospective cohort study included adult patients with ischemic stroke diagnosed during hospitalization at a comprehensive stroke center. Stroke recognition time was used as the reference point. Clinical characteristics, stroke severity, acute treatment, and in-hospital outcomes were analyzed. Primary outcomes were in-hospital mortality, discharge destination, and functional independence.
RESULTS: Fifty-two patients were included. Most strokes occurred in patients admitted for non-neurological conditions, mainly in surgical specialties. Stroke recognition was delayed in a relevant proportion of cases, and reperfusion therapy was infrequently performed, with no procedure-related complications. Moderate-to-severe strokes were common. In-hospital mortality was 9.6%, and functional status significantly declined from admission to discharge. Most patients received therapeutic care planning and were referred for rehabilitation.
CONCLUSION: In-hospital ischemic stroke predominantly affects patients hospitalized for non-neurological conditions and is frequently recognized late, limiting access to reperfusion therapies. These findings highlight important gaps in in-hospital stroke detection and support the implementation of structured rapid-response protocols.
OBJECTIVE: To characterize the clinical profile, care processes, and outcomes of patients with ischemic stroke occurring during hospitalization.
METHODS: The present retrospective cohort study included adult patients with ischemic stroke diagnosed during hospitalization at a comprehensive stroke center. Stroke recognition time was used as the reference point. Clinical characteristics, stroke severity, acute treatment, and in-hospital outcomes were analyzed. Primary outcomes were in-hospital mortality, discharge destination, and functional independence.
RESULTS: Fifty-two patients were included. Most strokes occurred in patients admitted for non-neurological conditions, mainly in surgical specialties. Stroke recognition was delayed in a relevant proportion of cases, and reperfusion therapy was infrequently performed, with no procedure-related complications. Moderate-to-severe strokes were common. In-hospital mortality was 9.6%, and functional status significantly declined from admission to discharge. Most patients received therapeutic care planning and were referred for rehabilitation.
CONCLUSION: In-hospital ischemic stroke predominantly affects patients hospitalized for non-neurological conditions and is frequently recognized late, limiting access to reperfusion therapies. These findings highlight important gaps in in-hospital stroke detection and support the implementation of structured rapid-response protocols.