Adult non-communicable disease mortality in Africa and Asia: evidence from INDEPTH Health and Demographic Surveillance System sites.
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Streatfield P Kim, Khan Wasif A, Bhuiya Abbas, Hanifi Syed M A, Alam Nurul, Bagagnan Cheik H, Sié Ali, Zabré Pascal, Lankoandé Bruno, Rossier Clementine, Soura Abdramane B, Bonfoh Bassirou, Kone Siaka, Ngoran Eliezer K, Utzinger Juerg, Haile Fisaha, Melaku Yohannes A, Weldearegawi Berhe, Gomez Pierre, Jasseh Momodou, Ansah Patrick, Debpuur Cornelius, Oduro Abraham, Wak George, Adjei Alexander, Gyapong Margaret, Sarpong Doris, Kant Shashi, Misra Puneet, Rai Sanjay K, Juvekar Sanjay, Lele Pallavi, Bauni Evasius, Mochamah George, Ndila Carolyne, Williams Thomas N, Laserson Kayla F, Nyaguara Amek, Odhiambo Frank O, Phillips-Howard Penelope, Ezeh Alex, Kyobutungi Catherine, Oti Samuel, Crampin Amelia, Nyirenda Moffat, Price Alison, Delaunay Valérie, Diallo Aldiouma, Douillot Laetitia, Sokhna Cheikh, Gómez-Olivé F Xavier, Kahn Kathleen, Tollman Stephen M, Herbst Kobus, Mossong Joël, Chuc Nguyen T K, Bangha Martin, Sankoh Osman A, Byass Peter
Аннотация
OBJECTIVE: To describe patterns of adult NCD mortality from INDEPTH Network sites across Africa and Asia, according to the WHO 2012 verbal autopsy (VA) cause categories, with separate consideration of premature (15-64 years) and older (65+ years) NCD mortality.
DESIGN: All adult deaths at INDEPTH sites are routinely registered and followed up with VA interviews. For this study, VA archives were transformed into the WHO 2012 VA standard format and processed using the InterVA-4 model to assign cause of death. Routine surveillance data also provide person-time denominators for mortality rates.
RESULTS: A total of 80,726 adult (over 15 years) deaths were documented over 7,423,497 person-years of observation. NCDs were attributed as the cause for 35.6% of these deaths. Slightly less than half of adult NCD deaths occurred in the 15-64 age group. Detailed results are presented by age and sex for leading causes of NCD mortality. Per-site rates of NCD mortality were significantly correlated with rates of HIV/AIDS-related mortality.
CONCLUSIONS: These findings present important evidence on the distribution of NCD mortality across a wide range of African and Asian settings. This comes against a background of global concern about the burden of NCD mortality, especially among adults aged under 70, and provides an important baseline for future work.