Revista da Associacao Medica Brasileira (1992) · 2025
Comparison of the effect of cardioplegic solutions used in cardiac surgery on myocardial protection.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод в очереди
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Padak Mahmut, Dikme Reşat, Ersöz Ezhar, Hacanlı Yasemin
Аннотация
OBJECTIVE: The aim of this retrospective study was to evaluate the effects of cardioplegic solutions on myocardial protection factors in patients undergoing cardiac surgery with cardiopulmonary bypass and to evaluate the relationship between these effects and early clinical outcomes.
METHODS: A total of 78 patients were included in the study. The data of patients who received del Nido cardioplegia (Group 1; n=39) and blood cardioplegia (Group 2; n=39) during the operation were grouped and compared. Preoperative and postoperative routine parameters such as creatine phosphokinase, troponin I, C-reactive protein, and demographic data were recorded, and statistical analyses were performed.
RESULTS: Perfusion time, cross-clamp time, act pump, preoperative C-reactive protein, preoperative creatine phosphokinase, preoperative troponin I, postoperative C-reactive protein, postoperative creatine phosphokinase, postoperative troponin I values were significantly different between del Nido and blood groups (p<0.05).
CONCLUSION: Del Nido cardioplegia provided myocardial protection and early postoperative favorable results compared to blood cardioplegia, which may make it a viable option for conventional cardiopulmonary bypass.
METHODS: A total of 78 patients were included in the study. The data of patients who received del Nido cardioplegia (Group 1; n=39) and blood cardioplegia (Group 2; n=39) during the operation were grouped and compared. Preoperative and postoperative routine parameters such as creatine phosphokinase, troponin I, C-reactive protein, and demographic data were recorded, and statistical analyses were performed.
RESULTS: Perfusion time, cross-clamp time, act pump, preoperative C-reactive protein, preoperative creatine phosphokinase, preoperative troponin I, postoperative C-reactive protein, postoperative creatine phosphokinase, postoperative troponin I values were significantly different between del Nido and blood groups (p<0.05).
CONCLUSION: Del Nido cardioplegia provided myocardial protection and early postoperative favorable results compared to blood cardioplegia, which may make it a viable option for conventional cardiopulmonary bypass.
Предметные рубрики MeSH
HumansCardioplegic SolutionsMaleRetrospective StudiesFemaleHeart Arrest, InducedMiddle AgedCardiopulmonary BypassTroponin IAgedCardiac Surgical ProceduresTreatment OutcomeCreatine KinaseC-Reactive ProteinTime FactorsPotassium ChlorideMannitolMyocardial Reperfusion InjuryLidocaineSolutionsElectrolytesMagnesium SulfateSodium Bicarbonate