Akusherstvo i ginekologiia · 2012
[Early detection of possibilities for preeclampsia using VEGF1 and other serum analysis].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Manolov V, Marinov B, Vasilev V
Аннотация
INTRODUCTION: The aim of our study is to establish an interaction between serum VEGF1 levels and possibilities of early detection of preeclampsia.
METHODS: For a period of three months we follow up 17 patients with preeclampsia in second trimester by measuring serum levels of VEGF1, PIGF and Inhibin A. A correlation between them was determined.
RESULTS: During our study we investigate 17 patients with preeclampsia and 35 as a control group. Significant differences between serum levels in too groups were established. Serum levels for VEGF1 above 158.5 pg/ml; Inhibin A above 98.50 ng/ml; PIGF levels above 30.01 pg/ml shows a diagnostic sensitivity 88.895 and diagnostic specificity 97.06% in prediction of preeclampsia.
CONCLUSION: Measurement of serum VEGF1, PIGF and Inhibin A levels are suitable for early prediction of possibilities for preeclampsia in second trimester. These results are the basis for further studies in this field.
METHODS: For a period of three months we follow up 17 patients with preeclampsia in second trimester by measuring serum levels of VEGF1, PIGF and Inhibin A. A correlation between them was determined.
RESULTS: During our study we investigate 17 patients with preeclampsia and 35 as a control group. Significant differences between serum levels in too groups were established. Serum levels for VEGF1 above 158.5 pg/ml; Inhibin A above 98.50 ng/ml; PIGF levels above 30.01 pg/ml shows a diagnostic sensitivity 88.895 and diagnostic specificity 97.06% in prediction of preeclampsia.
CONCLUSION: Measurement of serum VEGF1, PIGF and Inhibin A levels are suitable for early prediction of possibilities for preeclampsia in second trimester. These results are the basis for further studies in this field.