Fertility and sterility · 2001
Monopaternal superfecundation of quintuplets after transfer of two embryos in an in vitro fertilization cycle.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Amsalem H, Tsvieli R, Zentner B S, Yagel S, Mitrani-Rosenbaum S, Hurwitz A
Аннотация
OBJECTIVE: To present the first genetically proven identity of quintuplets in an IVF treatment cycle after transferring only two embryos.
DESIGN: Case report.
SETTING: IVF unit and obstetrics department of university-affiliated general hospital.
PATIENT(S): Twenty-five-year-old patient undergoing IVF treatment for unexplained infertility.
INTERVENTION(S): In vitro fertilization with intracytoplasmic sperm injection performed on 50% of oocytes, resulting in successful production of nine early-cleavage embryos. Transfer of two embryos on day 3 and freezing of the remaining embryos.
MAIN OUTCOME MEASURE(S): Development of five separate embryonic sacs. Fetal reduction of three embryos at 12 weeks of gestation.
RESULT(S): Successful completion of the twin pregnancy and full genetic analysis of the three embryos and the twins that were born at term.
CONCLUSION(S): Despite transferring only two embryos, superfecundation occurred, resulting in five embryos. Genetic analysis can be used to determine paternity and identity of all the embryos.
DESIGN: Case report.
SETTING: IVF unit and obstetrics department of university-affiliated general hospital.
PATIENT(S): Twenty-five-year-old patient undergoing IVF treatment for unexplained infertility.
INTERVENTION(S): In vitro fertilization with intracytoplasmic sperm injection performed on 50% of oocytes, resulting in successful production of nine early-cleavage embryos. Transfer of two embryos on day 3 and freezing of the remaining embryos.
MAIN OUTCOME MEASURE(S): Development of five separate embryonic sacs. Fetal reduction of three embryos at 12 weeks of gestation.
RESULT(S): Successful completion of the twin pregnancy and full genetic analysis of the three embryos and the twins that were born at term.
CONCLUSION(S): Despite transferring only two embryos, superfecundation occurred, resulting in five embryos. Genetic analysis can be used to determine paternity and identity of all the embryos.