BJOG : an international journal of obstetrics and gynaecology · 2020
A core outcome set for future endometriosis research: an international consensus development study.
СтатьяСистематический обзорConsensus StatementНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Duffy Jmn, Hirsch M, Vercoe M, Abbott J, Barker C, Collura B, Drake R, Evers Jlh, Hickey M, Horne A W, Hull M L, Kolekar S, Lensen S, Johnson N P, Mahajan V, Mol B W, Otter A-S, Puscasiu L, Rodriguez M B, Rombauts L, Vail A, Wang R, Farquhar C M, endo:outcomes - an International Collaboration Harmonising Outcomes and Outcome Measures for Endometriosis Research
Аннотация
OBJECTIVE: To develop a core outcome set for endometriosis.
DESIGN: Consensus development study.
SETTING: International.
POPULATION: One hundred and sixteen healthcare professionals, 31 researchers and 206 patient representatives.
METHODS: Modified Delphi method and modified nominal group technique.
RESULTS: The final core outcome set includes three core outcomes for trials evaluating potential treatments for pain and other symptoms associated with endometriosis: overall pain; improvement in the most troublesome symptom; and quality of life. In addition, eight core outcomes for trials evaluating potential treatments for infertility associated with endometriosis were identified: viable intrauterine pregnancy confirmed by ultrasound; pregnancy loss, including ectopic pregnancy, miscarriage, stillbirth and termination of pregnancy; live birth; time to pregnancy leading to live birth; gestational age at delivery; birthweight; neonatal mortality; and major congenital abnormalities. Two core outcomes applicable to all trials were also identified: adverse events and patient satisfaction with treatment.
CONCLUSIONS: Using robust consensus science methods, healthcare professionals, researchers and women with endometriosis have developed a core outcome set to standardise outcome selection, collection and reporting across future randomised controlled trials and systematic reviews evaluating potential treatments for endometriosis. TWEETABLE ABSTRACT: @coreoutcomes for future #endometriosis research have been developed @jamesmnduffy.
DESIGN: Consensus development study.
SETTING: International.
POPULATION: One hundred and sixteen healthcare professionals, 31 researchers and 206 patient representatives.
METHODS: Modified Delphi method and modified nominal group technique.
RESULTS: The final core outcome set includes three core outcomes for trials evaluating potential treatments for pain and other symptoms associated with endometriosis: overall pain; improvement in the most troublesome symptom; and quality of life. In addition, eight core outcomes for trials evaluating potential treatments for infertility associated with endometriosis were identified: viable intrauterine pregnancy confirmed by ultrasound; pregnancy loss, including ectopic pregnancy, miscarriage, stillbirth and termination of pregnancy; live birth; time to pregnancy leading to live birth; gestational age at delivery; birthweight; neonatal mortality; and major congenital abnormalities. Two core outcomes applicable to all trials were also identified: adverse events and patient satisfaction with treatment.
CONCLUSIONS: Using robust consensus science methods, healthcare professionals, researchers and women with endometriosis have developed a core outcome set to standardise outcome selection, collection and reporting across future randomised controlled trials and systematic reviews evaluating potential treatments for endometriosis. TWEETABLE ABSTRACT: @coreoutcomes for future #endometriosis research have been developed @jamesmnduffy.