Biosynthesis of vitamin C stabilized tin oxide nanoparticles and their effect on body weight loss in neonatal rats.

The green synthesis of tin oxide nanoparticles (SnO2 NPs) using vitamin C (Vc) as a reducing agent via a biosynthetic approach is described. The effect of Vc-stabilized SnO2 NPs on the body weight of neonatal rats is also studied. The prepared SnO2NPs were characterized using spectroscopic and microscopic instrumental techniques including transmission electron microscopy (TEM), UV-visible spectrophotometry (UV-vis), X-ray diffraction and Fourier transform infrared spectroscopy, which confirmed the formation of NPs. TEM images confirmed the formation of spherical NPs with a mean particle size of around 30nm. The body weight studies showed that vitamin-C stabilized SnO2 NPs promote a higher body weight gain compared to raw SnO2 NPs. It was also shown that Vc can counteract the decreased body weight caused by SnO2 NPs in neonatal rats.