Clinical Outcomes of Bail-Out Stenting After Drug-Coated Balloon Angioplasty: The International Multicenter BAILOUT Registry.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gitto Mauro, Leone Pier Pasquale, Rissanen Tuomas T, Corballis Natasha, Calamita Gianmaria, Tartaglia Francesco, Buono Andrea, Ferrone Marco, Ielasi Alfonso, Pismiankou Siamion, Rossi Marco Luciano, Merinopoulos Ioannis, Vassiliou Vassilios S, Salemme Luigi, Chiarito Mauro, Galasso Michele, Morosato Michele, Kyhl Kasper, Occhipinti Giovanni, Hinton Jonathan, Bacci Elodi, Vellucci Guido, Marchetta Marcello, De Micco Francesca, Regazzoli Damiano, Mangieri Antonio, Johnson Thomas, Ugo Fabrizio, Gasparini Gabriele, Reimers Bernhard, Kane Peter O', Sangiorgi Giuseppe Massimo, Stefanini Giulio G, Galli Stefano, Alfonso Fernando, Arroyo Diego, Sabaté Manel, Briguori Carlo, Tesorio Tullio, Mashayekhi Kambis, Maffeo Diego, Latib Azeem, Eccleshall Simon, Colombo Antonio
Аннотация
METHODS: The BAILOUT registry included consecutive patients undergoing bail-out DES implantation after DCB angioplasty at 17 European centers between 2011 and 2024. The primary end point was target lesion failure (TLF) at 1 year, defined as the composite of target lesion revascularization, target vessel myocardial infarction, and cardiac death. The TLF rate was compared with a performance goal of 7.0% for an upfront DES-only strategy, derived from a meta-analysis of contemporary randomized controlled trials.
RESULTS: A total of 733 patients were included, accounting for 5.5% of all DCB-based percutaneous coronary interventions. At 1 year, the cumulative TLF incidence in the overall population was 7.0% (95% CI, 5.2%-9.3%), which was comparable to the performance goal (P=0.916). This was mainly driven by target lesion revascularization (4.1%), while cardiac death and target vessel myocardial infarction occurred both in 1.9% of patients. The incidence of stent thrombosis was 0.6%. Independent predictors of 1-year TLF included lesion length (hazard ratio, 1.02 per mm increase [95% CI, 1.01-1.03]; P<0.001), moderate-to-severe calcification (hazard ratio, 2.82 [95% CI, 1.48-5.40]; P=0.002), and the use of paclitaxel- versus sirolimus-coated balloons (hazard ratio, 1.99 [95% CI, 1.01-4.05]; P=0.048).
CONCLUSIONS: In cases of suboptimal angiographic results after DCB angioplasty, bail-out DES implantation is safe, with no increased risk of TLF at 1 year compared with the expected performance goal for an upfront DES-only strategy.