Internal medicine (Tokyo, Japan) · 2022
FLAMES with Elevated Myelin Basic Protein Followed by Myelitis.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
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Hokama Hiroyuki, Sakamoto Yuki, Hayashi Toshiyuki, Hatake Seira, Takahashi Mizuho, Kodera Hiroto, Kutsuna Akihito, Nito Chikako, Nakane Shunya, Nagayama Hiroshi, Takahashi Toshiyuki, Kimura Kazumi
Аннотация
The pathophysiology of unilateral cortical fluid-attenuated inversion recovery (FLAIR)-hyperintense lesions in anti-myelin oligodendrocyte glycoprotein (MOG)-associated encephalitis with seizures (FLAMES) is unclear. A 26-year-old man was referred because of a seizure. FLAIR showed an increased signal intensity and swelling of the right frontal cortex. His symptoms and imaging abnormalities were improved after intravenous methylprednisolone therapy. MOG antibody was detected both in serum and cerebrospinal fluid (CSF). Therefore, the patient was diagnosed with FLAMES. Myelin basic protein (MBP) was elevated in CSF. The high MBP value in the CSF in the present case suggested that demyelination as well as inflammation can occur in some FLAMES patients.