Медицинская библиотека · Urology · 2017

Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication.

Godoy-Santos Alexandre Leme, Bruschini Homero, Cury Jose, Srougi Miguel, de Cesar-Netto Cesar, Fonseca Lucas F, Maffulli Nicola

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Аннотация

OBJECTIVE

To evaluate the current evidence and to identify associated risk factors that increase the incidence of this complication. Fluoroquinolone (FQ) has been considered the first-line therapy for uncomplicated urinary infections. FQ has been associated with Achilles tendon disorders, especially during the first month of treatment.

METHODS

Data sources searched included PubMed, MEDLINE, and Scopus from January 1988 to June 2017.

RESULTS

A total of 79 articles were used, with ciprofloxacin representing the most common drug.

CONCLUSION

We found that male gender, advanced age, normal body mass index, chronic renal failure, and concurrent use of corticosteroids increase the risk of Achilles tendon disorders.

Для цитирования: Godoy-Santos Alexandre Leme, Bruschini Homero, Cury Jose, Srougi Miguel, de Cesar-Netto Cesar, Fonseca Lucas F, Maffulli Nicola. Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication.. Urology. 2017. DOI: 10.1016/j.urology.2017.10.017.

Предметные рубрики MeSH

Achilles Tendon Adult Age Factors Case-Control Studies Female Fluoroquinolones Follow-Up Studies Humans Incidence Male Middle Aged Retrospective Studies Rupture, Spontaneous Severity of Illness Index Sex Factors Tendinopathy Urinary Tract Infections

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