JAAPA : official journal of the American Academy of Physician Assistants · 2023
Drugs in primary care that may alter COVID-19 risk and severity.
СтатьяНазвание и аннотация: Перевод в очереди
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Luu Brent, Wijesinghe Sampath, Kassem Tarek, Lien Justin, Luu Darrick, Wijesinghe Rynee, Luu Leianna, Kayingo Gerald
Аннотация
This article describes drugs used in primary care that could alter patients' risk for and severity of COVID-19. The risks and benefits of each drug class were differentiated according to the strength of evidence from 58 selected randomized controlled trials, systematic reviews, and meta-analyses. Most of the studies reported on drugs affecting the renin-angiotensin-aldosterone system. Other classes included opioids, acid suppressants, nonsteroidal anti-inflammatory drugs, corticosteroids, vitamins, biguanides, and statins. Current evidence has not fully differentiated drugs that may increase risk versus benefits in COVID-19 infection. Further studies are needed in this area.