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DOI 10.1038/s41372-023-01643-2

Медицинская библиотека · Journal of perinatology : official journal of the California Perinatal Association · 2023

Social disadvantage during pregnancy: effects on gestational age and birthweight.

Luby Joan L, England Sarah K, Barch Deanna M, Warner Barbara B, Rogers Cynthia, Smyser Christopher D, Triplett Regina, Arora Jyoti, Smyser Tara A, Slavich George M, Zhao Peinan, Stout Molly, Herzog Erik, Miller J Philip

СтатьяПоддержка исследования: вне правительства СШАПоддержка NIH: внешняя программаПеревод в очереди

Аннотация

OBJECTIVE

Whether psychosocial adversity during pregnancy impacts fetal health outcomes at birth remains underexplored. This is a critical issue given significant social disadvantage and psychosocial stress faced by pregnant women worldwide.

STUDY

DESIGN

Measures of social disadvantage and psychological factors, and medical/reproductive and nutritional health status in pregnant women were obtained at each trimester. Using Structural Equation Modeling (SEM), we investigated the relationship of forms of adversity to each other and to infant gestational age, and birthweight.

RESULTS

Among 399 singletons, Social Disadvantage significantly predicted gestational age (p = 0.003), and residual birthweight (p = 0.006). There was a 0.4 week decrease in gestational age and a 3% decrease in birthweight for each standard deviation increase in Social Disadvantage.

CONCLUSION

Significant negative effects of social adversity on the developing fetus were found. Notably, these effects emerged despite good prenatal care and after accounting for maternal age and medical reproductive risk factors.

Для цитирования: Luby Joan L, England Sarah K, Barch Deanna M, Warner Barbara B, Rogers Cynthia, Smyser Christopher D, Triplett Regina, Arora Jyoti, Smyser Tara A, Slavich George M, Zhao Peinan, Stout Molly, Herzog Erik, Miller J Philip. Social disadvantage during pregnancy: effects on gestational age and birthweight.. Journal of perinatology : official journal of the California Perinatal Association. 2023. DOI: 10.1038/s41372-023-01643-2.

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