Antimicrobial resistance and infection control · 2025
Sepsis outbreak following a probable extrinsic contamination of propofol by Escherichia coli, Geneva, 2024.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Petrucci Roberta, Allaoua Amir, Metsini Aliki, Cherkaoui Abdessalam, Vu Diem-Lan, Lazarevic Vladimir, Perreard Delphine, Haroutunian Nechan, Garcin Sophie, Grosgurin Olivier, Vernaz Nathalie, Harbarth Stephan, Regard Simon, Schrenzel Jacques, Cassini Alessandro
Аннотация
Over a 14-day period, four patients developed sepsis within hours of undergoing endoscopic procedures at a gastroenterology outpatient clinic in Geneva (Switzerland), triggering an urgent epidemiological investigation upon notification to authorities. The case clustering raised concerns about a iatrogenic source, prompting a coordinated public health response. This report outlines the investigation led by the Geneva Health Authorities in collaboration with the medical team, emergency care providers, infection prevention specialists, and the bacteriology laboratory at Geneva University Hospitals. A multidisciplinary team, including an epidemiologist, a pharmacist and an infection prevention specialist, conducted an on-site investigation the day after the outbreak was identified, highlighting a probable extrinsic contamination of propofol by Escherichia coli.