Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
Feasibility study of the Four-Session Cognitive-Behavioral Therapy-based Psychological Intervention Program for women with HER2-positive metastatic breast cancer.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Szekeres Tamás, Balázs Máté Ádám, Madarász Bálint, Póti Zsuzsa, Urbán Róbert, Dank Magdolna, Vizin Gabriella
Аннотация
PURPOSE: Although targeted therapies have prolonged survival in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer, the resulting chronic disease trajectory is frequently accompanied by substantial psychological burden. This study aimed to conduct a preliminary investigation into the feasibility and psychological outcomes of a low-intensity, group-based cognitive-behavioral therapy intervention (CBT-OP-4) among women receiving palliative care.
METHODS: A prospective feasibility study without a control group was undertaken involving 13 female participants (mean age = 63 years, SD = 8.05), all diagnosed with HER2-positive metastatic breast cancer. The four-session CBT-based group intervention targeted key psychological domains. Self-reported measures of distress, depression, anxiety, perceived stigma, self-compassion, and locus of control were administered pre- and post-intervention. Feasibility and acceptability were further examined via semi-structured qualitative interviews and standardized patient satisfaction instruments.
RESULTS: Following the intervention, pre-post improvements were observed in psychological distress, depressive symptoms, and perceived stigma. In parallel, participants demonstrated an increase in self-compassion. Overall, the program was rated as highly acceptable, with participants emphasizing the relevance and applicability of the intervention content within their illness context.
CONCLUSION: Findings from this preliminary study suggest that the CBT-OP-4 program is a feasible and acceptable psycho-oncological intervention for women with advanced-stage HER2-positive breast cancer receiving palliative care. The results offer initial empirical support for the incorporation of structured, evidence-based psychological interventions into the routine psychosocial management of this patient population.
METHODS: A prospective feasibility study without a control group was undertaken involving 13 female participants (mean age = 63 years, SD = 8.05), all diagnosed with HER2-positive metastatic breast cancer. The four-session CBT-based group intervention targeted key psychological domains. Self-reported measures of distress, depression, anxiety, perceived stigma, self-compassion, and locus of control were administered pre- and post-intervention. Feasibility and acceptability were further examined via semi-structured qualitative interviews and standardized patient satisfaction instruments.
RESULTS: Following the intervention, pre-post improvements were observed in psychological distress, depressive symptoms, and perceived stigma. In parallel, participants demonstrated an increase in self-compassion. Overall, the program was rated as highly acceptable, with participants emphasizing the relevance and applicability of the intervention content within their illness context.
CONCLUSION: Findings from this preliminary study suggest that the CBT-OP-4 program is a feasible and acceptable psycho-oncological intervention for women with advanced-stage HER2-positive breast cancer receiving palliative care. The results offer initial empirical support for the incorporation of structured, evidence-based psychological interventions into the routine psychosocial management of this patient population.