Clinical, sociodemographic and environmental factors impact post-COVID-19 syndrome.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Ferreira Juliana Carvalho, Moreira Tiana C Lopes, de Araújo Adriana Ladeira, Imamura Marta, Damiano Rodolfo F, Garcia Michelle L, Sawamura Marcio Vy, Pinna Fabio R, Guedes Bruno F, Gonçalves Fabio A Rodrigues, Mancini Marcio, Burdmann Emmanuel A, da Silva Filho Demóstenes Ferreira, Polizel Jefferson Lordello, Bento Ricardo F, Rocha Vanderson, Nitrini Ricardo, de Souza Heraldo Possolo, Levin Anna S, Kallas Esper G, Forlenza Orestes V, Busatto Geraldo F, Batistella Linamara R, de Carvalho Carlos R Ribeiro, Mauad Thais, Gouveia Nelson, HCFMUSP COVID-19 Study Group
Аннотация
METHODS: We included patients hospitalized between March to August 2020 who were alive six months after hospitalization. We collected individual and clinical characteristics during hospitalization and at follow-up assessed ten symptoms with standardized scales, 19 yes/no symptoms, a functional status and a quality-of-life scale and performed four clinical tests. We examined individual exposure to greenspace and air pollution and considered neighbourhood´s population density and socioeconomic conditions as contextual factors in multilevel regression analysis.
RESULTS: We included 749 patients with a median follow-up of 200 (IQR = 185-235) days, and 618 (83%) had at least one of the ten symptoms measured with scales. Pain (41%), fatigue (38%) and posttraumatic stress disorder (35%) were the most frequent. COVID-19 severity, comorbidities, BMI, female sex, younger age, and low socioeconomic position were associated with different symptoms. Exposure to ambient air pollution was associated with higher dyspnoea and fatigue scores and lower functional status.
CONCLUSIONS: We identified a high frequency of persistent symptoms among COVID-19 survivors that were associated with clinical, sociodemographic, and environmental variables. These findings indicate that most patients recovering from COVID-19 will need post-discharge care, and an additional burden to health care systems, especially in LMICs, should be expected.