[Fibrocystic disease of the breast in autopsy cases with special reference to the age frequency distribution of epithelial hyperplasia and its relation to liver cirrhosis].

A histological examination of 306 breast tissues taken consecutively from autopsied Japanese women aged from 12 to 104 during the period between 1973 and 1984, excluding breast cancer cases, was undertaken. Two peaks at the ages of 40 to 44 and 55 to 59 were seen in the age-frequency distribution of fibrocystic disease (FCD), blunt duct adenosis (BDA), and duct papillomatosis (DP). There was no significant difference in the frequency of FCD, BDA, and apocrine metaplasia between the cases of liver cirrhosis and those without any hepatic disorders (controls). On the other hand, DP was seen more frequently and in higher degree in those with liver cirrhosis as compared with controls.