Head & neck · 2025
Rates of ICU Delirium After Microvascular Free Tissue Transfer Reconstruction of the Oral Cavity and Oropharynx.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Nesmith William, Fakurnejad Shayan, Gillard Danielle, Wai Katherine, Xu Mary Jue, Likhterov Ilya, George Jonathan, Ryan William, El-Sayed Ivan, Ha Patrick, Park Andrea, Seth Rahul, Knott P Daniel, Heaton Chase
Аннотация
BACKGROUND: Microvascular free tissue transfer (MFTT) is the standard in the reconstruction of major head and neck defects, but involves extended hospital stays and an increased risk of post-operative delirium (POD). What risk factors increase the risk of POD in patients undergoing MFTT, and subsequent complications?
METHODS: Retrospective cohort study of 168 patients undergoing MFTT following ablation of oral cavity or oropharyngeal cancer. Patient demographic data, operative data, post-operative ventilatory support needs, post-operative complications, and post-operative sedation and analgesic needs were collected, and the association with POD was evaluated.
RESULTS: POD was significantly associated with opioid (p = 0.0018) and sedation requirements (p < 0.001), postoperative return to the OR (p = 0.002) and medical complications (p = 0.033). There was no association with the rate of MFTT failure (p > 0.05).
CONCLUSION: In MFTT patients, opioid and sedative administration are potentially modifiable factors that may be able to reduce POD incidence and optimize the postoperative course of patients undergoing MFTT.
METHODS: Retrospective cohort study of 168 patients undergoing MFTT following ablation of oral cavity or oropharyngeal cancer. Patient demographic data, operative data, post-operative ventilatory support needs, post-operative complications, and post-operative sedation and analgesic needs were collected, and the association with POD was evaluated.
RESULTS: POD was significantly associated with opioid (p = 0.0018) and sedation requirements (p < 0.001), postoperative return to the OR (p = 0.002) and medical complications (p = 0.033). There was no association with the rate of MFTT failure (p > 0.05).
CONCLUSION: In MFTT patients, opioid and sedative administration are potentially modifiable factors that may be able to reduce POD incidence and optimize the postoperative course of patients undergoing MFTT.