[IMMUNOMORPHOLOGICAL FEATURES OF THE PLACENTA IN MULTIPLE PREGNANCIES].

Placentas clinical and immunological research in women with multiple pregnancy, noted the presence of morphological and functional, immunopathologic changes of varying severity. It is proved that in women with miscarriage at the level of multiple pregnancy placental insufficiency depends on the blood supply to the placenta and the nature of the inflammatory manifestations. The morphological pattern of placental disorders in miscarriage was revealed that the morphological features of placental insufficiency in non-infectious factors of miscarriage are early changes in the vessels of the decidua in a spasm, obliteration of the lumen of the spiral arteries, a decrease of vascular villous tree, reducing the amount of chorionic epithelium and peripheral trophoblast, increased maternal and fetal deposits fibrinoid. Thanks to the research will be possible to form a clear vision that would allow on the basis of public spending immunomorfological features pathogenetically substantiated therapy prenatal complications arising from multiple pregnancies.