[Progress and extensive meaning of mammalian target of rapamycin involved in restoration of nervous system injury].

OBJECTIVE

To review the possible mechanisms of the mammalian target of rapamycin (mTOR) in the neuronal restoration process after nervous system injury.

METHODS

The related literature on mTOR in the restoration of nervous system injury was extensively reviewed and comprehensively analyzed.

RESULTS

mTOR can integrate signals from extracellular stress and then plays a critical role in the regulation of various cell biological processes, thus contributes to the restoration of nervous system injury.

CONCLUSION

Regulating the activity of mTOR signaling pathway in different aspects can contribute to the restoration of nervous system injury via different mechanisms, especially in the stress-induced brain injury. mTOR may be a potential target for neuronal restoration mechanism after nervous system injury.