Clinical laboratory · 2015
Systemic mastocytosis with recurrent anaphylactic shock and multiple organ dysfunction failure.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Chen Guoshu, Chen Li, Qin Xiaohua, Xie Xiaoling, Li Guowei, Xu Bing
Аннотация
BACKGROUND: Systemic mastocytosis (SM) is a rare neoplasm. The symptoms of this disease vary among patients. The authors describe a rare case of SM with recurrent anaphylactic shock and multiple organ dysfunction failure.
METHODS: Hematologic investigation, bone marrow aspirate and biopsy, and cytogenetic analysis were performed.
RESULTS: The patient was rescued with positive treatment, administered on prednisolone and H1/H2-receptor blocking agents. Corticosteroid and IFN-α treatment have no significant effect on tumor burden, but no more anaphylactic shock occurred.
CONCLUSIONS: Cladribine and imatinib are recommended to treat SM patients to obtain a better therapeutic effect. Maybe allogeneic hematopoietic stem cell transplantation is a cure for SM.
METHODS: Hematologic investigation, bone marrow aspirate and biopsy, and cytogenetic analysis were performed.
RESULTS: The patient was rescued with positive treatment, administered on prednisolone and H1/H2-receptor blocking agents. Corticosteroid and IFN-α treatment have no significant effect on tumor burden, but no more anaphylactic shock occurred.
CONCLUSIONS: Cladribine and imatinib are recommended to treat SM patients to obtain a better therapeutic effect. Maybe allogeneic hematopoietic stem cell transplantation is a cure for SM.