Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2011
Selective cerebellar and basal ganglia injury in neuroleptic malignant syndrome.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Lyons Jennifer L, Cohen Adam B
Аннотация
BACKGROUND AND PURPOSE: High core body temperatures have been shown to selectively damage the cerebellum and basal ganglia in malignant hyperthermia, but involvement of both areas in neuroleptic malignant syndrome (NMS) has not been described.
METHODS: Here, we report a case of acute cerebellar and basal ganglia injury by magnetic resonance imaging (MRI) in the setting of NMS. We discuss the pathophysiology, both of NMS and hyperthermic brain injury.
RESULTS: MRI showed new restricted diffusion in cerebellar hemispheres bilaterally and right basal ganglia when compared with brain MRI obtained 1 month prior. T2 FLAIR hyperintensities corresponding to diffusion restriction were also seen in the cerebellum.
CONCLUSIONS: Both the basal ganglia and cerebellum can be injured selectively in NMS.
METHODS: Here, we report a case of acute cerebellar and basal ganglia injury by magnetic resonance imaging (MRI) in the setting of NMS. We discuss the pathophysiology, both of NMS and hyperthermic brain injury.
RESULTS: MRI showed new restricted diffusion in cerebellar hemispheres bilaterally and right basal ganglia when compared with brain MRI obtained 1 month prior. T2 FLAIR hyperintensities corresponding to diffusion restriction were also seen in the cerebellum.
CONCLUSIONS: Both the basal ganglia and cerebellum can be injured selectively in NMS.