Effect of eight-week curcumin supplementation with endurance training on glycemic indexes in middle age women with type 2 diabetes in Iran, A preliminary study.

BACKGROUND AND AIMS: The purpose of this study was to determine the effects of curcumin supplementation & endurance training on glycemic indexes in middle-aged women with type 2 diabetes.

METHODS

40 middle-aged women with type 2 diabetes were randomly divided into four groups (control, curcumin, training & curcumin + training). Endurance training protocol included running on treadmill for eight weeks, three sessions per week and each session for 45-60 min, with a maximum intensity of 50-70% of MHR. The experimental groups received a supplementation of curcumin as a daily dose of 80 mg curcumin soft gel for 8 weeks while the control group was subjected to no supplementation or exercise during this period. One day before and one day after the eight-week experimental period, blood samples were taken from the subjects to measure the glycemic indexes, including fasting blood glucose, glycosylated hemoglobin, and serum insulin levels. T-test and two-way covariance analysis tests were used for analyzing the findings at a significant level of less than 0.05.

RESULTS

Eight weeks of curcumin supplementation and endurance training, whether done separately or simultaneously, significantly reduced fasting blood glucose, glycosylated hemoglobin and serum insulin levels (P < 0.05). The combination of curcumin supplementation and endurance training compared to the other two interventions caused a significant further decrease in these glycemic indexes (P < 0.05).

CONCLUSION

The findings of this study showed that eight weeks of curcumin supplementation and endurance training helped each other in improving the glycemic indexes of women with type 2 diabetes.