A single transurethral Macroplastique injection as primary treatment for stress incontinence in women.

The clinical records of 102 women were analysed to estimate the success rate of a single transurethral Macroplastique (Uroplasty BV, Netherlands) injection for the treatment of stress incontinence. We then compared the results of those who had had the injection as primary treatment (71/102) with those women who had undergone previous failed incontinence surgery (31/102). The overall success rate was 68% following a single injection of Macroplastique at a mean follow-up period of 3.2 months; the success rate was obtained by including all patients who were either cured or markedly improved requiring no further intervention. The success rate of those who had had previous surgery was 71% and for the primary treatment group it was 66%. This difference was not statistically significant. These results suggest a potential role of Macroplastique transurethral injection as primary treatment for genuine stress incontinence in women.