Internal medicine (Tokyo, Japan) · 2019
Diffusion-weighted Whole-body Imaging with Background Body Signal Suppression (DWIBS) as a Novel Imaging Modality for Disease Activity Assessment in Takayasu's Arteritis.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Oguro Eri, Ohshima Shiro, Kikuchi-Taura Akie, Murata Atsuko, Kuzuya Kentaro, Okita Yasutaka, Matsuoka Hidetoshi, Teshigawara Satoru, Yoshimura Maiko, Yoshida Yuji, Isoda Kentaro, Kudo-Tanaka Eriko, Harada Yoshinori, Kaminou Toshio, Saeki Yukihiko
Аннотация
A 26-year-old woman with Takayasu's arteritis (TAK) experienced back and neck pain during tocilizumab (TCZ) treatment. The levels of C-reactive protein were normal, and ultrasonography revealed no significant changes. Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) showed signal enhancement in the walls of several arteries. Contrast computed tomography showed arterial inflammation in the same lesion. After increasing the dose of prednisolone and TCZ, all signal enhancements decreased and continued to decrease, as observed on days 76 and 132. Thus, DWIBS may be a novel imaging modality for assessing the disease activity of TAK, particularly during follow-up.
Предметные рубрики MeSH
AdultAnti-Inflammatory AgentsAntibodies, Monoclonal, HumanizedBack PainC-Reactive ProteinCarotid Artery, CommonCarotid StenosisComputed Tomography AngiographyDose-Response Relationship, DrugFemaleHumansInfusions, IntravenousMagnetic Resonance ImagingMultimodal ImagingNeck PainPrednisoloneRecurrenceSubclavian Steal SyndromeTakayasu ArteritisUltrasonographyWhole Body Imaging