Continuum (Minneapolis, Minn.) · 2026
Neurologic Manifestations of Rheumatologic Disease.
СтатьяКлинический случайОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Bhattacharyya Shamik
Аннотация
OBJECTIVE: This article provides readers with a foundational approach to the diagnosis and treatment of neurologic syndromes that occur in patients with rheumatologic diseases.
LATEST DEVELOPMENTS: Neuroimaging findings such as the central vein sign on MRI to distinguish the white matter lesions of multiple sclerosis from those of systemic lupus erythematosus (SLE), the trident sign on axial postcontrast spine MRI in patients with sarcoid myelopathy, and vessel wall imaging to differentiate central nervous system vasculitis from vasculopathy, can improve diagnostic precision in patients with neurorheumatologic disorders. Treatment of neurologic complications of rheumatologic disease is guided largely by case series but increasingly incorporates targeted therapies such as infliximab for neurosarcoidosis and neuro-Behçet syndrome.
ESSENTIAL POINTS: Systemic rheumatologic diseases can cause diverse neurologic symptoms that can be causally related, treatment induced, or comorbid but unrelated. Diagnosis relies on clinical criteria, serology, imaging, and, if these are unrevealing or inconclusive, tissue biopsy.
LATEST DEVELOPMENTS: Neuroimaging findings such as the central vein sign on MRI to distinguish the white matter lesions of multiple sclerosis from those of systemic lupus erythematosus (SLE), the trident sign on axial postcontrast spine MRI in patients with sarcoid myelopathy, and vessel wall imaging to differentiate central nervous system vasculitis from vasculopathy, can improve diagnostic precision in patients with neurorheumatologic disorders. Treatment of neurologic complications of rheumatologic disease is guided largely by case series but increasingly incorporates targeted therapies such as infliximab for neurosarcoidosis and neuro-Behçet syndrome.
ESSENTIAL POINTS: Systemic rheumatologic diseases can cause diverse neurologic symptoms that can be causally related, treatment induced, or comorbid but unrelated. Diagnosis relies on clinical criteria, serology, imaging, and, if these are unrevealing or inconclusive, tissue biopsy.