[Professional practices and commitments in the care of people living with HIV/AIDS].

This study sought to understand the professional practices in caring for people living with HIV/AIDS considering the global commitments to end the AIDS epidemic by 2030 in a priority municipality of Santa Catarina, Brazil. Qualitative research based on the constructivist branch of grounded theory was carried out in primary health and specialized care with in-depth interviews with 45 participants, including healthcare providers, managers, and people living with HIV/AIDS, from 2020 to 2021. Data analysis obtained the core category "Unveiling local professional practices aimed at global commitments to confront the HIV/AIDS epidemic", supported by seven subcategories that evince the expansion of timely rapid testing with reception and counseling, guarantee of access, early diagnosis and immediate start of antiretroviral therapy, engagement with the therapeutic regimen and its contradictions, social stigmatization, fear and overcoming HIV/AIDS, and the limitations of information systems. Practices related to preventive and clinical aspects stood out, with nurses playing a leading role in them. Coping with the social stigmatization by people living with HIV/AIDS experience still features an incipient approach in several dimensions: themselves, their families, healthcare providers, and social life. Overcoming the HIV/AIDS epidemic requires articulated and equitable strategies that consider the social determinants of health, expand access, and promote the well-being of people living with HIV/AIDS.