Ophthalmology · 2001
The prevalence of cupping in end-stage arteritic and nonarteritic anterior ischemic optic neuropathy.
Клиническое исследованиеСравнительное исследованиеСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Danesh-Meyer H V, Savino P J, Sergott R C
Аннотация
OBJECTIVE: To evaluate the prevalence of cupping in arteritic anterior ischemic optic neuropathy (AAION) and nonarteritic anterior ischemic optic neuropathy (NAION).
DESIGN: Retrospective, observational case series.
PARTICIPANTS: Three hundred one patients.
METHODS: Review of clinical records and color fundus photographs.
MAIN OUTCOME MEASURES: Photographic and clinical interpretation of optic nerve appearance.
RESULTS: Ninety-two patients with AAION and 102 with NAION were included in the study. Disc photographs of 42 patients (48%) with AAION and 32 patients (31%) with NAION were available for reassessment. These were presented in a masked fashion along with a random sample of 27 disc pairs considered to be 'normal' and 27 disc pairs with 'established glaucoma' according to two examiners. Cupping was present in 92% of eyes with AAION secondary to giant cell arteritis and in 2% of eyes with NAION (kappa = 0.96; P < 0.001).
CONCLUSIONS: The end-stage optic disc appearance in AAION secondary to giant cell arteritis is cupping, whereas segmental or diffuse pallor without cupping is the typical disc appearance after NAION.
DESIGN: Retrospective, observational case series.
PARTICIPANTS: Three hundred one patients.
METHODS: Review of clinical records and color fundus photographs.
MAIN OUTCOME MEASURES: Photographic and clinical interpretation of optic nerve appearance.
RESULTS: Ninety-two patients with AAION and 102 with NAION were included in the study. Disc photographs of 42 patients (48%) with AAION and 32 patients (31%) with NAION were available for reassessment. These were presented in a masked fashion along with a random sample of 27 disc pairs considered to be 'normal' and 27 disc pairs with 'established glaucoma' according to two examiners. Cupping was present in 92% of eyes with AAION secondary to giant cell arteritis and in 2% of eyes with NAION (kappa = 0.96; P < 0.001).
CONCLUSIONS: The end-stage optic disc appearance in AAION secondary to giant cell arteritis is cupping, whereas segmental or diffuse pallor without cupping is the typical disc appearance after NAION.