Oral diseases · 2025
Speech and Swallowing Disorders in Adolescent and Young Adults With Oral Cavity Cancer.
СтатьяНазвание и аннотация: Перевод в очереди
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Deng Wei, Zhao Guiyi, Xiao Yudong, Guo Kaixin, Zhang Sien, Liao Guiqing, Yang Le, Liang Yujie
Аннотация
OBJECTIVE: To evaluate the speech and swallowing function and recovery status in adolescent and young adult (AYAs) patients with oral cavity cancer (OCC).
METHODS: A cohort study was conducted in AYAs patients with OCC from August 2019 to April 2021. The swallowing and speech functions were evaluated by M.D. Anderson dysphagia inventory (MDADI), 10-item eating assessment tool (EAT-10) and speech handicap index (SHI) at pretreatment and postoperative stages. Multiple linear regression and linear mixed models were employed.
RESULTS: A total of 661 patients were enrolled, including 143 AYAs and 518 individuals aged ≥ 40. The preoperative total scores of MDADI, EAT-10, and SHI were worse in AYAs patients. AYAs patients with advanced T stage (T3-T4) before surgery exhibited worse scores for MDADI, EAT-10, and SHI. All patients presented the poorest outcomes within the initial 3 months postoperatively. However, a more rapid recovery trend of swallowing and speech function was demonstrated in the AYAs. Adjuvant radiotherapy/chemotherapy, advanced T stage (T3-T4), tracheostomy, or flap reconstruction were key risk factors of impairing speech and swallowing functions in AYAs patients.
CONCLUSIONS: AYAs experience worse speech and swallowing function in the pretreatment stage and generally exhibit a higher potential for recovery.
METHODS: A cohort study was conducted in AYAs patients with OCC from August 2019 to April 2021. The swallowing and speech functions were evaluated by M.D. Anderson dysphagia inventory (MDADI), 10-item eating assessment tool (EAT-10) and speech handicap index (SHI) at pretreatment and postoperative stages. Multiple linear regression and linear mixed models were employed.
RESULTS: A total of 661 patients were enrolled, including 143 AYAs and 518 individuals aged ≥ 40. The preoperative total scores of MDADI, EAT-10, and SHI were worse in AYAs patients. AYAs patients with advanced T stage (T3-T4) before surgery exhibited worse scores for MDADI, EAT-10, and SHI. All patients presented the poorest outcomes within the initial 3 months postoperatively. However, a more rapid recovery trend of swallowing and speech function was demonstrated in the AYAs. Adjuvant radiotherapy/chemotherapy, advanced T stage (T3-T4), tracheostomy, or flap reconstruction were key risk factors of impairing speech and swallowing functions in AYAs patients.
CONCLUSIONS: AYAs experience worse speech and swallowing function in the pretreatment stage and generally exhibit a higher potential for recovery.