Ginekologia polska · 1998
[Carrier of numerical chromosome abnormalities in infertile married couples].
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Dudkiewicz J, Wawrzkiewicz A, Adamowicz R, Waksmański B, Muszer M
Аннотация
OBJECTIVES: Genetic anomalies are one of many conditions causing infertility.
DESIGN: The aim of the study was to define the frequency of numerical chromosome aberrations in infertile married couples.
MATERIALS AND METHODS: Metaphasal chromosomes were analysed by G-T-G stration in 650 patients, i.e. 325 married couples. Chromosomes for testing had been obtained from peripheral blood lymphocytes.
RESULTS: Of all women and men, numerical chromosome anomalies were found in 14 married couples (4.1%). The aberrations were connected with female factors in 8 couples (2.3%), and with male factors in 6 (1.8%).
CONCLUSIONS: Results of the study indicate that diagnostic procedure for infertility should preferably include cytogenetic examinations as well.
DESIGN: The aim of the study was to define the frequency of numerical chromosome aberrations in infertile married couples.
MATERIALS AND METHODS: Metaphasal chromosomes were analysed by G-T-G stration in 650 patients, i.e. 325 married couples. Chromosomes for testing had been obtained from peripheral blood lymphocytes.
RESULTS: Of all women and men, numerical chromosome anomalies were found in 14 married couples (4.1%). The aberrations were connected with female factors in 8 couples (2.3%), and with male factors in 6 (1.8%).
CONCLUSIONS: Results of the study indicate that diagnostic procedure for infertility should preferably include cytogenetic examinations as well.