[Carrier of numerical chromosome abnormalities in infertile married couples].

OBJECTIVES

Genetic anomalies are one of many conditions causing infertility.

DESIGN

The aim of the study was to define the frequency of numerical chromosome aberrations in infertile married couples.

MATERIALS AND

METHODS

Metaphasal chromosomes were analysed by G-T-G stration in 650 patients, i.e. 325 married couples. Chromosomes for testing had been obtained from peripheral blood lymphocytes.

RESULTS

Of all women and men, numerical chromosome anomalies were found in 14 married couples (4.1%). The aberrations were connected with female factors in 8 couples (2.3%), and with male factors in 6 (1.8%).

CONCLUSIONS

Results of the study indicate that diagnostic procedure for infertility should preferably include cytogenetic examinations as well.