Diagnostic Value of Chest Computed Tomography Scan for Identification of Foreign Body Aspiration in Children: A Systematic Review and Meta-analysis.
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Goodarzy Babak, Rahmani Erfan, Farrokhi Mehrdad, Tavakoli Reza, Moghadam Fard Atousa, Ranjbaran Ghaleh Mohadese, Ghalichebaf Yazdi Yeganeh, Amani Beni Reza, Ghadirzadeh Erfan, Afrazeh Fatemeh, Alipour Khabir Yalda, Alipour Khabir Sevda, Bakhtiyari Paria, Atighi Javaneh, Mahjoubi Mohammad, Momeni Zahra, Jalayeri Hediyeh, Hosseini Mohammad Hossein, Hoorshad Behnam, Tavakoli Mehdi, Seifi Sepideh, Momeni Hamidreza, Mirbolook Amirhossein, Esmaili Jobani Alireza, Mohammadi Visroud Mozhdeh, Najafi Aboulfazl, Hosseini Zahrasadat, Aboulhassanzadeh Sobhan, Ajami Negar, Ramezani Sahel, Manavi Mahdokht Sadat, Safdari Sina, Fallahian Amirali, Azimi Habib, Zahedpasha Reza, Ranjbar Ehsan, Kahrizi Mohammad Saeed, Zare Lahijan Lida
Аннотация
METHODS: From inception to May 2024, a systematic search was carried out across multiple databases including Medline, Scopus, and Web of Science, considering published papers in English language. Quality assessment of the included studies was performed using seven domains of Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2).
RESULTS: The systematic literature search yielded 7203 articles. The pooled sensitivity and specificity of chest CT scan for identification of FBA were 0.99 (95% CI: 0.98-0.99) and 0.97 (95% CI: 0.96-0.98), respectively. The pooled positive likelihood ratio was 10.12 (95% CI: 4.59-22.20), and pooled negative likelihood ratio was 0.05 (95% CI: 0.02-0.1). Furthermore, the area under the summarized receiver operating characteristic (SROC) curve was 0.98.
CONCLUSION: Our meta-analysis revealed that despite high heterogeneity, in the diagnostic characteristics of chest CT scan among studies, it has high diagnostic value in identifying FBA in suspected pediatric cases.