The Caribbean, Central and South America Network for HIV Epidemiology: 20 Years of HIV Research in the Region.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Castilho Jessica L, Duda Stephany N, Shepherd Bryan E, Sterling Timothy R, Person Anna K, Rebeiro Peter F, Wester William C, Koethe John R, Carlson Jesse, Pellegrino Rachael A, Jayathilake Karu, Maruri Fernanda, Riley Hilary Vansell, Amaral Amanda Garcia De Matos, Figueiredo Marina Cruvinel, Ranadive Paridhi, Turner Megan, Amorim Gustavo, Myers Vickie, Burgess Heather, Tu Shengxin, Du Liping, Shi Danni, Liang Zhouhui, Liu Kaixing, Yan Chao, Grinsztejn Beatriz, Veloso Valdilea G, Luz Paula M, Cardoso Sandra Wagner, Friedman Ruth, Moreira Ronaldo I, Pedrosa Monica Derrico, Perazzo Hugo, Moreira Rodrigo, Ribeiro Maria Pia Diniz, Pereira Mario Sergio, Jalil Emilia Moreira, Torres Thiago Silva, Coutinho Carolina, Silva Mayara Secco Torres, Victoriano Flaviana Pavan, Pinto Jorge, Ferreira Flavia, Maia Marcelle, Bocardi Victoria, Caporali Julia, Fonseca Flavia, Westin Mateus, Succi Regina Célia de Menezes, Machado Daisy Maria, Gouvêa Aida de Fátima Barbosa, Bononi do Carmo Fabiana, Cortes Claudia P, Rodriguez Maria Fernanda, Castillo-Rozas Gabriel, Paredes Fabio, Estadella Georgina, Pape Jean William, Rouzier Vanessa, Marcelin Adias, Bernadin Jodany, Cadet Stanley, Luque Marco Tulio, Varela Diana, Chavez Magda, Mailhot Ada, Gotuzzo Eduardo, Mejia Fernando, Carriquiry Gabriela, Mochizaki Claudia Nuñez, Ramirez Brenda Crabtree, Madero Juan Sierra, Vega Yanink Caro, Iñiguez Álvaro López, Menchelli Ana Fernanda Ramos, Murra Paola Alarcón, Coello Geovanna, Nájera Guadalupe Muñuzuri, Benavides Rodrigo Ville, Mejía Jessica, Bejarano Távata, Sierra Nancy, Fink Valeria, Cahn Florencia, Aristegui Ines, Figueroa Maria Ines, Doudtchitzky Nicolas, Mariani Javier, Ceschel Mariela, Mernies Gissella, Nava Agustin, Cesar Carina, Cahn Pedro, Caribbean, Central and South America network for HIV Epidemiology (CCASAnet) of the International epidemiology Databases to Evaluate AIDS (IeDEA)
Аннотация
METHODS: CCASAnet data are collected using standardized data elements, including demographic information, HIV disease history, laboratory data, antiretroviral regimens, co-infections and comorbidities. Data collection has expanded to include prospective data such as substance use, antiretroviral therapy adherence, geriatric syndromes and tuberculosis treatment. All clinical sites retain ownership of their data, and CCASAnet data contribute as able to global IeDEA-level projects. Robust data quality initiatives and statistical methods have strengthened the cohort.
RESULTS: CCASAnet consists of nine clinics across seven countries (Argentina, Brazil, Chile, Haiti, Honduras, Mexico and Peru). Over 61,000 adults and children living with HIV have contributed observational data through December 2023. While CD4 at enrolment has remained largely unchanged, time to antiretroviral therapy initiation has decreased, retention in care has improved and the proportion with undetectable HIV RNA has dramatically increased. Co-infections and AIDS-defining malignancies remain a cause of morbidity and mortality, but non-communicable diseases have also increased. Overall mortality trends in the region have improved over time, with some notable exceptions.
CONCLUSIONS: Underscoring the importance of maintaining longitudinal collaborations and data collection, CCASAnet remains the largest source of high-quality data for HIV epidemiology in Latin America and serves as an important evidence base for informing global and regional policy and stakeholder decisions related to the HIV epidemic.