The relation between visual hallucinations and visual evoked potential in Parkinson disease.

OBJECTIVE

The pathophysiology of hallucinations in Parkinson disease is poorly understood. This study investigated the relation between visual hallucination and visual evoked potentials (VEPs) in Parkinson disease.

METHODS

Nineteen patients with Parkinson disease were studied. The authors divided patients into 2 groups: patients with visual hallucinations (VH group) and those without visual hallucinations (no-VH group). VEPs using a checkerboard stimulus were recorded under a drug-free state.

RESULTS

On multivariate regression analysis, only the average P100 latency was selected and remained significant after the backward elimination method.

CONCLUSION

The authors demonstrated a close association between visual hallucinations and elongated VEP latency in Parkinson disease. VEPs may become one of the predictors for visual hallucination.