Gynecology and minimally invasive therapy · 2019
The Management of Heterotopic Pregnancy with Transvaginal Ultrasound-Guided Local Injection of Absolute Ethanol.
СтатьяНазвание и аннотация: Перевод в очереди
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Liu Conghui, Jiang Hong, Ni Feng, Liu Ying, Zhang Wenxiang, Feng Cuie
Аннотация
AIMS: The aim of the study is to present five cases of heterotopic pregnancy (HP) patients who received transvaginal ultrasound-guided local injection of absolute ethanol (AE).
SETTINGS AND DESIGN: This was a case series and literature review in Reproductive Medicine Center of the 105th Hospital of the People's Liberation Army.
MATERIALS AND METHODS: Five primary infertile women who underwent assisted reproductive technology were diagnosed with HP and treated with local injection of AE (1.0-2.5 ml) under transvaginal ultrasound guidance. The size of intrauterine (IU) and ectopic sacs and the level of serum beta-human chorionic gonadotropin as well as pregnancy outcomes were monitored after treatment.
STATISTICAL ANALYSIS USED: Not applicable.
RESULTS: Four of five cases presented with lack of Doppler flow in the injected area after AE injection. Meanwhile, IU pregnancy proceeded well after treatment and delivered a normal newborn. One case received emergency surgery 3 h after local injection of 2.5 ml AE because of the rupture of ectopic gestational sac (GS). An early abortion was identified 7 days after the surgery.
CONCLUSIONS: Transvaginal ultrasound-guided local injection of AE is an alternative nonsurgical treatment for HP, yet overdose injection of AE will increase the risk of ectopic GS rupture.
SETTINGS AND DESIGN: This was a case series and literature review in Reproductive Medicine Center of the 105th Hospital of the People's Liberation Army.
MATERIALS AND METHODS: Five primary infertile women who underwent assisted reproductive technology were diagnosed with HP and treated with local injection of AE (1.0-2.5 ml) under transvaginal ultrasound guidance. The size of intrauterine (IU) and ectopic sacs and the level of serum beta-human chorionic gonadotropin as well as pregnancy outcomes were monitored after treatment.
STATISTICAL ANALYSIS USED: Not applicable.
RESULTS: Four of five cases presented with lack of Doppler flow in the injected area after AE injection. Meanwhile, IU pregnancy proceeded well after treatment and delivered a normal newborn. One case received emergency surgery 3 h after local injection of 2.5 ml AE because of the rupture of ectopic gestational sac (GS). An early abortion was identified 7 days after the surgery.
CONCLUSIONS: Transvaginal ultrasound-guided local injection of AE is an alternative nonsurgical treatment for HP, yet overdose injection of AE will increase the risk of ectopic GS rupture.