Plastic and reconstructive surgery. Global open · 2025
Outcome of Prepectoral Direct-to-Implant Breast Reconstruction With the Poly-4-hydroxybutyrate Wrap.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Sorenson Thomas J, Boyd Carter J, Hemal Kshipra, Park Jenn J, Amro Chris, Vernice Nicholas, Lakatta Alexis, Cohen Oriana, Choi Mihye, Karp Nolan
Аннотация
BACKGROUND: Prepectoral direct-to-implant (DTI) breast reconstruction has gained popularity for reducing postoperative pain, animation deformity, and the number of surgical procedures. However, the limited vascularized tissue overlying the implant presents challenges. This study evaluated mean 18-month outcomes in prepectoral DTI patients using a poly-4-hydroxybutyrate (P4HB) wrap designed to optimize reconstructive results.
METHODS: We retrospectively reviewed all consecutive patients who underwent prepectoral DTI breast reconstruction with our P4HB-implant construct. Data were collected via chart review.
RESULTS: There were 50 patients with 87 breasts included. The mean (± SD) age of patients was 52.7 (± 11.7) years, and the median (interquartile range) body mass index (BMI) was 23 (5) kg/m2. The mean (± SD) follow-up time was 18.1 (± 5.1) months. Thirty (30 of 50, 60%) patients did not require further procedures beyond the index operation. No patients had implant malposition/dystopia. Of patients requiring a subsequent operation, the majority (12 of 20, 60%) of operations were for aesthetic optimization. Eight (8 of 87, 9.2%) breasts required a subsequent operation due to complications with 4 (4 of 87, 4.6%) of these breasts requiring removal of the construct. Increased BMI and age were found to significantly decrease the odds of rippling (odds ratios 0.73 and 0.89, respectively), and increased BMI was also found to significantly increase the odds of major complications (odds ratio 1.21).
CONCLUSIONS: This is the first study reporting mean 18-month P4HB outcomes in prepectoral DTI breast reconstruction at full hydrolysis. Most patients did not require revisional procedures during the follow-up period, and reoperations were primarily for aesthetic concerns. These findings suggest that P4HB is an effective adjunct for implant stabilization in breast reconstruction.
METHODS: We retrospectively reviewed all consecutive patients who underwent prepectoral DTI breast reconstruction with our P4HB-implant construct. Data were collected via chart review.
RESULTS: There were 50 patients with 87 breasts included. The mean (± SD) age of patients was 52.7 (± 11.7) years, and the median (interquartile range) body mass index (BMI) was 23 (5) kg/m2. The mean (± SD) follow-up time was 18.1 (± 5.1) months. Thirty (30 of 50, 60%) patients did not require further procedures beyond the index operation. No patients had implant malposition/dystopia. Of patients requiring a subsequent operation, the majority (12 of 20, 60%) of operations were for aesthetic optimization. Eight (8 of 87, 9.2%) breasts required a subsequent operation due to complications with 4 (4 of 87, 4.6%) of these breasts requiring removal of the construct. Increased BMI and age were found to significantly decrease the odds of rippling (odds ratios 0.73 and 0.89, respectively), and increased BMI was also found to significantly increase the odds of major complications (odds ratio 1.21).
CONCLUSIONS: This is the first study reporting mean 18-month P4HB outcomes in prepectoral DTI breast reconstruction at full hydrolysis. Most patients did not require revisional procedures during the follow-up period, and reoperations were primarily for aesthetic concerns. These findings suggest that P4HB is an effective adjunct for implant stabilization in breast reconstruction.