The deadliest lung lobe in COVID-19: a retrospective cohort study of elderly patients hospitalized for COVID-19.

INTRODUCTION

The relationship between which lung lobe is affected on the chest X-ray (CXR) performed at the Emergency Department (ED) and mortality from COVID-19 has not been studied. With this in mind, the present study aimed to discern which lung lobe was the one with the highest associated mortality rate in the elderly population.

METHODS

Information was collected from the 2020 hospital admissions records of our hospital. Our cohort consists of 300 admissions.

RESULTS

The presence of the left lower lobe (RR = 1.6; 95% CI: 1.1-2.4) and right middle lobe involvement (RR = 1.8; 95% CI: 1.2-2.7) on CXR at the ED were both predictive factors of in-hospital mortality. Right middle lobe involvement on CXR at the ED was the risk factor with the highest relative risk value (RR = 1.8). Furthermore, right middle lobe involvement on CXR at ED was a predictor for persistent organ failure (RR = 1.7; 95% CI: 1.2-2.3), respiratory failure (RR = 1.7; 95% CI: 1.2-2.4) and acute kidney injury (RR = 1.5; 95% CI: 1.2-2). The isolated right middle lobe involvement on CXR at ED was a risk factor for in-hospital mortality (RR = 2.6; 95% CI = 1.8-3.7). However, the affected right middle lobe along with another/other lobe/s was a null factor.

CONCLUSION

Right middle lobe involvement was an independent predictor of in-hospital mortality.