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DOI 10.1016/j.biopha.2022.113089

Медицинская библиотека · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022

COVID-19 and diabetes: Association intensify risk factors for morbidity and mortality.

Sharma Prateek, Behl Tapan, Sharma Neelam, Singh Sukhbir, Grewal Ajmer Singh, Albarrati Ali, Albratty Mohammed, Meraya Abdulkarim M, Bungau Simona

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Аннотация

Diabetes is a condition that affects a large percentage of the population and it is the leading cause of a wide range of costly complications. Diabetes is linked to a multi-fold increase in mortality and when compared to non-diabetics, the intensity and prevalence of COVID-19 ailment among diabetic individuals are more. Since its discovery in Wuhan, COVID-19 has grown rapidly and shown a wide range of severity. Temperature, lymphopenia, non-productive cough, dyspnoea, and tiredness are recognized as the characteristic of individuals infected with COVID-19 disease. In COVID-19 patients, diabetes and other related comorbidities are substantial predictors of disease and mortality. According to a recent study, SARS-CoV-2 (the virus responsible for covid-19 disease) may also lead to direct pancreatic harm, which could aggravate hyperglycemia and potentially cause the establishment of diabetes in formerly non-diabetic individuals. This bidirectional association of COVID-19 and diabetes load the burden on health care professionals throughout the world. It is recommended that gliptin medications be taken moderately, blood glucose levels must be kept under control, ACE inhibitors should be used in moderation, decrease the number of avoidable hospitalizations, nutritional considerations, and some other prevention measures, such as immunization, are highly recommended. SARS-CoV-2 may cause pleiotropic changes in glucose homeostasis, which could exacerbate the pathophysiology of pre-existing diabetes or result in new disease processes.

Для цитирования: Sharma Prateek, Behl Tapan, Sharma Neelam, Singh Sukhbir, Grewal Ajmer Singh, Albarrati Ali, Albratty Mohammed, Meraya Abdulkarim M, Bungau Simona. COVID-19 and diabetes: Association intensify risk factors for morbidity and mortality.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022. DOI: 10.1016/j.biopha.2022.113089.

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