[Study on the chemical constituents from fresh roots of Euphorbia fischeriana].

OBJECTIVE

To study the chemical constituents in ethyl acetate fraction from the Euphorbia fischeriana.

METHODS

The compounds were isolated by silica gel column chromatography and HPLC, and their structures were elucidated by means of spectral analyses.

RESULTS

Fourteen compounds were identified as 2,4-dihydroxy-6-methoxy-3-methylacetophenone (1), 12-deoxyphorbol-13-hexadecanoate (2), ethylgallate (3), esculetin (4), 2,4-dihydroxy-6-methoxy-acetophenone (5), 12-deoxyphorbol-13-acetate (6), 12-deoxyphorbol-13,20-diacetete (7), jolkinolide B (8), 17-hydroxyjolkinolide B (9), 17-hydroxy-jolkinolide A (10), langduin C (11), 3-methylp-hydroxybenzoic acid (12), methyl gallate (13), 3, 3'-diacetyl-pyridine-4,4'-dimethoxy-2, 2', 6, 6'-tetrahydroxydiphenylmethane (14).

CONCLUSION

Compounds 3, 5, 12, 13 are isolated from this plant for the first time.