Transsexual development of a patient with Klinefelter's syndrome.

Although the psychosexual development of patients with Klinefelter's syndrome is often delayed, the sexual identity is generally male. This paper reports on a 56-year-old patient whose initially good psychosocial integration gave way to a transsexual development with a meanwhile clearcut female sexual identity as the consequence of a personal crisis situation. This case report illustrates the interaction of biological and psychodynamic etiological factors.