Osteoporosis and sarcopenia · 2023
Effect of romosozumab in premenopausal women with severe osteoporosis and anorexia nervosa.
СтатьяНазвание и аннотация: Перевод в очереди
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Fujimoto Kazuki, Maki Narumi, Hashiba Daisuke, Maeyama Toshifumi, Nakagawa Ryosuke, Arai Hajime, Ohtori Seiji
Аннотация
OBJECTIVES: This study aims to investigate the effects of romosozumab on bone mineral density (BMD) and bone metabolism.
METHODS: In this retrospective case series, romosozumab was administered to 5 premenopausal female patients with osteoporosis and anorexia nervosa with fragility fractures. BMD and bone turnover marker changes were investigated at 6 months and 1 year after administering romosozumab.
RESULTS: BMD increased and high-turnover bone metabolism decreased 6 months and 1 year after administering romosozumab.
CONCLUSIONS: Romosozumab is useful for treating osteoporosis in patients with anorexia nervosa.
METHODS: In this retrospective case series, romosozumab was administered to 5 premenopausal female patients with osteoporosis and anorexia nervosa with fragility fractures. BMD and bone turnover marker changes were investigated at 6 months and 1 year after administering romosozumab.
RESULTS: BMD increased and high-turnover bone metabolism decreased 6 months and 1 year after administering romosozumab.
CONCLUSIONS: Romosozumab is useful for treating osteoporosis in patients with anorexia nervosa.