Journal of clinical immunology · 2017
The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies.
СтатьяНазвание и аннотация: Перевод в очереди
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Bousfiha Aziz, Jeddane Leïla, Picard Capucine, Ailal Fatima, Bobby Gaspar H, Al-Herz Waleed, Chatila Talal, Crow Yanick J, Cunningham-Rundles Charlotte, Etzioni Amos, Franco Jose Luis, Holland Steven M, Klein Christoph, Morio Tomohiro, Ochs Hans D, Oksenhendler Eric, Puck Jennifer, Tang Mimi L K, Tangye Stuart G, Torgerson Troy R, Casanova Jean-Laurent, Sullivan Kathleen E
Аннотация
Since the 1990s, the International Union of Immunological Societies (IUIS) PID expert committee (EC), now called Inborn Errors of Immunity Committee, has published every other year a classification of the inborn errors of immunity. This complete catalog serves as a reference for immunologists and researchers worldwide. However, it was unadapted for clinicians at the bedside. For those, the IUIS PID EC is now publishing a phenotypical classification since 2013, which proved to be more user-friendly. There are now 320 single-gene inborn errors of immunity underlying phenotypes as diverse as infection, malignancy, allergy, auto-immunity, and auto-inflammation. We herein propose the revised 2017 phenotypic classification, based on the accompanying 2017 IUIS Inborn Errors of Immunity Committee classification.