Journal of cancer policy · 2026
A pilot study on the acceptability and feasibility of HPV self-sampling for cervical cancer screening among women attending urban hospitals in Kumasi, Ghana.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Adankwah Ernest, Mensah Adwoa Bemah Boamah, Konney Thomas, Nones Madalyn, Ekekpi Rita Ziem, Okyere Joshua, Basing Laud Anthony, Boadu Kwame Ofori, Eduah Felicia Maame Efua, Virnig Beth, Kulasingam Shalini
Аннотация
BACKGROUND: Self-sampled HPV testing followed by timely treatment has shown promise in increasing screening uptake and improving cervical cancer outcomes. However, in low-resource countries like Ghana, its adoption and sustainability face significant challenges.
METHODS: This cross-sectional pilot study comprised a convenience sample of women presenting at two healthcare facilities in Ghana: Kumasi South Hospital and South Suntreso Hospital. Following consent, a pre-and post-collection survey was administered by a trained study nurse to examine women's preferences and experiences with self-sampling. Participants were then asked to self-collect an HPV sample followed by a clinician-conducted exam using visual inspection with acetic acid (VIA). Samples were tested for HPV genotypes using the Seegene Anyplex HPV28 Test.
RESULTS: Sixty women were enrolled. After performing HPV self-collection, 91.7 % (n = 55) stated that they would prefer self-sampling instead of a clinician-collected Pap smear. Prior to the self-collection process, 40.0 % (24 women) gave high ratings for the overall acceptability of HPV self-collection. This increased to 86.7 % (52 women) after the self-collection process. Of the 60 women, 25 % (15/60) tested positive for HPV and 6.7 % (4/60) were confirmed positive by VIA examination. Overall agreement between the two procedures was fair (κ=0.24).
CONCLUSIONS: This pilot study supports the feasibility of HPV self-sampling and its potential to increase access to cervical screening in Ghana.
METHODS: This cross-sectional pilot study comprised a convenience sample of women presenting at two healthcare facilities in Ghana: Kumasi South Hospital and South Suntreso Hospital. Following consent, a pre-and post-collection survey was administered by a trained study nurse to examine women's preferences and experiences with self-sampling. Participants were then asked to self-collect an HPV sample followed by a clinician-conducted exam using visual inspection with acetic acid (VIA). Samples were tested for HPV genotypes using the Seegene Anyplex HPV28 Test.
RESULTS: Sixty women were enrolled. After performing HPV self-collection, 91.7 % (n = 55) stated that they would prefer self-sampling instead of a clinician-collected Pap smear. Prior to the self-collection process, 40.0 % (24 women) gave high ratings for the overall acceptability of HPV self-collection. This increased to 86.7 % (52 women) after the self-collection process. Of the 60 women, 25 % (15/60) tested positive for HPV and 6.7 % (4/60) were confirmed positive by VIA examination. Overall agreement between the two procedures was fair (κ=0.24).
CONCLUSIONS: This pilot study supports the feasibility of HPV self-sampling and its potential to increase access to cervical screening in Ghana.