Laser-assisted Analgesic and Vasoconstrictive Drug Delivery During and After Fractional CO2 Resurfacing: A Novel Technique to Enhance Procedural Tolerance and Recovery.

BACKGROUND

Fractional carbon dioxide (CO2) laser resurfacing is an effective treatment of various dermatological conditions. Pain, erythema, and edema following fractional ablative resurfacing are key limitations to patient comfort and satisfaction.

OBJECTIVE

This study aims to describe a novel technique using laser-assisted drug delivery to administer a combination of local anesthetics and epinephrine both during and after fractional CO2 laser resurfacing, enhancing procedural anesthesia and postprocedure recovery.

METHODS

We performed an observational review of patient-reported pain scores and clinical outcomes in patients treated with application of an anesthetic spray during and after fractional CO2 laser resurfacing treatments.

RESULTS

Patients demonstrated an average of 68% reduction in pain scores (p<0.001) scores postapplication, with additional clinical improvements in postlaser erythema and edema.

CONCLUSION

Laser-assisted drug delivery of local anesthetics and epinephrine after fractional ablative resurfacing appears to offer a simple, low-cost adjunct for improving patient experience and recovery. Further investigation is warranted.