The quality-of-life implications of helplessness in middle-age and older Nigerians living with HIV.

Antiretroviral therapies (ARTs) have reduced mortality among people living with HIV (PLWH) in Nigeria. Nonetheless, there is limited research on the impact of perceived helplessness on the wellbeing of PLWH in Nigeria. This study examined the effect of perceived helplessness on middle-age and older PLWH using health-related quality of life (HRQoL), subjective health (SH), and subjective cognitive decline (SCD) as outcomes related to wellbeing. We invited 150 participants, all of whom completed a self-administered questionnaire assessing the variables of interest and key sociodemographic characteristics. Multiple linear regression models were fit to examine the relationship between perceived helplessness and wellbeing, accounting for relevant covariates such as age, sex, relationship status etc. Results showed that higher perceived helplessness was associated with lower physical HRQoL (B = -0.275, p < 0.001), lower mental HRQoL (B = -0.18, p < 0.001), better SH (B = 0.010, p < 0.001) and higher reports of SCD (B = 0.443, p < 0.001). PLWH in Nigeria are exposed to stressors that diminish their sense of control and increase their risk for poor wellbeing. The findings underscore the need for interventions to ameliorate perceived helplessness, thereby improving health and wellbeing among aging adult PLWH in Nigeria.