[Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape].
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Hassenstein Max J, Aarabi Ghazal, Ahnert Peter, Becher Heiko, Franzke Claus-Werner, Fricke Julia, Krause Gérard, Glöckner Stephan, Gottschick Cornelia, Karch André, Kemmling Yvonne, Kerrinnes Tobias, Lange Berit, Mikolajczyk Rafael, Nieters Alexandra, Ott Jördis J, Ahrens Wolfgang, Berger Klaus, Meinke-Franze Claudia, Gastell Sylvia, Günther Kathrin, Greiser Karin Halina, Holleczek Bernd, Horn Johannes, Jaeschke Lina, Jagodzinski Annika, Jansen Lina, Jochem Carmen, Jöckel Karl-Heinz, Kaaks Rudolf, Krist Lilian, Kuß Oliver, Langer Susan, Legath Nicole, Leitzmann Michael, Lieb Wolfgang, Loeffler Markus, Mangold Nina, Michels Karin B, Meisinger Christa, Obi Nadia, Pischon Tobias, Schikowski Tamara, Schipf Sabine, Schulze Matthias B, Stang Andreas, Waniek Sabina, Wirkner Kerstin, Willich Stefan N, Castell Stefanie
Аннотация
OBJECTIVES: The aim was to describe the tools used to assess infectious diseases and to present initial data on infectious disease frequencies, as well as to relate the GNC assessment tools to data collection methods in other studies in Germany.
METHODS: As part of the baseline examination, questions regarding infectious diseases were administered using both an interview and a self-administered touchscreen questionnaire. Data from the initial 101,787 GNC participants were analysed.
RESULTS: In the interview, 0.2% (HIV/AIDS) to 8.6% (shingles) of respondents reported ever having a medical diagnosis of shingles, postherpetic neuralgia (in cases where shingles was reported), hepatitis B/C, HIV/AIDS, tuberculosis or sepsis if treated in hospital. In the questionnaire, 12% (cystitis) to 81% (upper respiratory tract infections) of respondents reported having experienced at least one occurrence of upper or lower respiratory tract infections, gastrointestinal infections, cystitis or fever within the past 12 months.
OUTLOOK: The cross-sectional analyses of data and tools presented here - for example on determinants of susceptibility to self-reported infections - can be anticipated from the year 2021 onward. Beyond that, more extensive research into infectious disease epidemiology will follow, particularly once analyses of GNC biological materials have been performed.